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Olga S. Latinovic

Olga S. Latinovic

Principal Investigator
Institute of Human Virology
Baltimore, United States

Biography

Olga S. Latinovic received her M.Sc (2001), Ph. D (2006) from Lehigh University, USA, where she was awarded multiple times the Sherman Fairchild scholarship for outstanding academic performance. She received her MBA degree in Healthcare management from the University of Baltimore, MD USA in 2020. As of 2011, she is a principal investigator working at the Institute of Human Virology (IHV) led by Robert C. Gallo, M.D. at the University of Maryland, School of Medicine in Baltimore, MD, USA. She heads the Laboratory for the Pathogen and Host Cell Interactions and IHV’s Imaging facility. She is developing novel antiviral therapy strategies using various HIV entry inhibitors, with a focus on understanding antiviral synergistic activity and its mechanism between CCR5 antagonists and CCR5 antibodies. She is developing super resolution microscopy methods in order to visualize direct CCR5 interactions with CCR5 blockers, as well as CCR5 conformational changes permissive for virus entry. In order to validate antiretroviral drugs, her most recent research interest and published work is in humanized mouse models that are reconstituted with human hematopoietic cells. These models mimic the natural course of HIV infection in humans and allow for a further and more comprehensive validation of drug treatment in a convenient in vivo model. Ultimately drugs so validated can be candidates for future clinical trials in humans. She wrote the book Micromechanics and Structure of Soft and Biological Materials, as a sole author and published by Verlag Dr. Muller in 2010, and she co-authored the book Handbook of Photonics for Biomedical Engineering published by Springer-Verlag in 2014. Her lectured Virus Entry course for the grad students at the Department of Microbiology and Immunology at the University of Maryland, School of Medicine (2011-2018) and she has lectured at various national/international conferences. She serves as a Reviewer and is on the Editorial Board of several scientific journals. She is a member of several national and international scientific societies.

Research Interest

Her research interest focuses on Virology,